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艾美捷科技代理Technoclone 品牌。

Technoclone重要的止血和纤维蛋白溶解领域诊断测试、设备和研究产品的生产商。除了拥有全面的常规和专科测试产品组合,Technoclone还改进了其全自动Ceveron alpha/alpha TGA仪器,推出了新的Ceveron 100系列仪器。凭借超过10年的全自动凝血生成测试经验,新的Ceveron 100系列产品将TGA测试能力提高了50%。此外,通过在顶级系统Ceveron s100上使用淬火技术,Technoclone提供了全球首款全自动止血分析仪,能够同时运行常规和专科测试,包括全自动凝血生成、ADAMTS13活性和因子XIII活性。

Technoclone产品和平台包括:

(1)针对凝血和纤溶系统成分的单克隆抗体:这些单克隆抗体用于检测凝血和纤溶系统中的特定成分,有助于了解止血功能状态。

(2)全自动凝血酶生成测试:这是一项先进的体外诊断测试,用于评估凝血酶的生成情况,有助于诊断凝血障碍和其他相关疾病。

(3)测试、校准器和控制器:Technoclone提供一系列全球测试和校准工具,确保诊断设备的准确性和可靠性。

(4)因子分析:用于分析凝血和纤溶系统中的各种因子,帮助医生确定患者是否存在特定的凝血障碍或疾病。

(5)血管性血友病和TTP(血栓性血小板减少性紫癜)相关测试:提供针对这些特定疾病的诊断测试,有助于早期发现和有效治疗。

(6)抗凝治疗监测:为接受抗凝治疗的患者提供监测工具,以确保治疗的有效性和安全性。

(7)辅助试剂和系列研究型产品:为满足科研和特殊诊断需求,提供一系列辅助试剂和研究型产品。

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艾美捷科技代理Gene Tools品牌


Gene Tools是一家生产和销售Morpholino Anti-sense oligos(反义寡核苷酸)的公司,其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成,为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具,已被广泛用于:阻断靶mRNA 翻译 (下调基因);诱导RNA选择性剪接 (下调或上调基因);阻断 miRNA;阻断病毒 RNA;阻断 non-coding RNA。


▍Morpholino介绍

Morpholino属于第三代反义寡核苷酸,主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用,目前已经广泛用于发育生物学和细胞学实验中,并取得了非常好的实验效果。

Morpholino以吗啉环类似物为基本骨架,这种独特的结构特性使得Morpholino 具有以下几个特点:

● 与其他类型的反义寡核苷酸相比,Morpholino 能更好地抵抗核酸酶的作用;

● Morpholino 与靶序列结合后通过空间位阻效应发挥作用, 不激活RNaseH,不引起目标基因mRNA 的降解 ;

● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译,针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切,得到不 同的转录本,可以方便地用于目标基因结构域的突变研究;

● 与靶序列结合能力强,可以渗入mRNA 的二级结构, 并且特异性好。

配合Morpholino 的使用,Gene Tools公司开发了相应的递送系统,可以安全、高效地将Morpholino 输送至胞内,因此,Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外,Morpholino 可以标上荧光基团、亲和标签以及活性反应基团,以供不同的研究需要。

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▍Gene Tools公司产品介绍

● Custom Morpholino:可以根据目标基因序列定制设计并合成Morpholino,用于体外细胞实验或某些直接显微注射的模型(如斑马鱼、非洲爪蟾胚胎)。

● Vivo-Morpholino:适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。通过特殊的末端修饰,提高了其穿透细胞膜进入组织细胞的能力,使得在成年动物(主要是小鼠、大鼠)中进行系统性基因功能研究成为可能。

● Prepared Control Oligos:根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。


产品名称Short DescriptionOligo sequenceSKU
Standard Control Oligo Negative control oligoCCTCTTACCTCAGTTACAATTTATAPCO-StandardControl-100
Vivo-Morpholino Standard Control OligoNegative Vivo-Morpholino control oligoCCTCTTACCTCAGTTACAATTTATAPCO-VivoStandardControl-100
Random Control Oligo 25-N25-base random sequence mixtureNNNNNNNNNNNNNNNNNNNNNNNNNPCO-RandomControl-25N-100
Zebrafish p53 oligoDanio rerio apoptosis suppression oligoGCGCCATTGCTTTGCAAGAATTGPCO-ZebrafishP53-100
Zebrafish Chordin Positive Control OligoDanio rerio Chordin positive control oligoATCCACAGCAGCCCCTCCATCATCCPCO-ZebrafishChordin-100-F
Clawed Frog Beta Catenin Positive Control OligoXenopus laevis Beta Catenin antisense oligoTTTCAACCGTTTCCAAAGAACCAGGPCO-BetaCatenin-100-F
Green Fluorescent Protein Positive ControlTranslation blocker for GFP targetACAGCTCCTCGCCCTTGCTCACCATPCO-GFPControl-100
Vivo-Morpholino GFP Positive ControlTranslation blocker for GFP target (Vivo-Morpholino)ACAGCTCCTCGCCCTTGCTCACCATPCO-VivoGFPControl-100
Fluoresceinated Vivo-Morpholino Std ControlNegative Vivo-Morpholino control oligo with 5'FluoresceinCCTCTTACCTCAGTTACAATTTATAPCO-FluorVivoStandardControl-100-F


● Endo-Porter:为了解决Morpholino在体外培养细胞中摄取效率低的问题,Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。



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艾美捷科技代理AxisPharm品牌全系列产品


AxisPharm是一家专业的分析服务提供商,致力于为科学研究界和工业界提供高质量的分析服务。凭借先进的仪器设备和专业的技术团队,AxisPharm在生物分析、化学分析和质量控制领域树立了良好的声誉。AxisPharm公司的产品线包括:PEG 连接子、用于药物递送的脂质、荧光染料、单击化学试剂、聚聚乙二醇,共聚物、可裂解的连接子、抗体和抗体药物偶联物ADC、ADC 有效载荷、细胞生物学试剂、脱氧核糖核酸、修饰语、探针、合成肽、目标特定链接器、硫醇反应性接头、酸反应性连接子、胺反应性连接子、羰基反应性连接子、探针、修饰符。


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▍AxisPharm产品线

● PEG连接子:聚合物聚乙二醇是多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 用于药物递送的脂质:在药物递送系统中起着至关重要的作用,特别是在脂质体、脂质纳米颗粒或脂质胶束等脂质制剂中。脂质提供结构稳定性,增强药物溶解度,实现控释,并促进靶向药物递送。

● 荧光染料:也称为荧光团或荧光探针,是吸收一种波长的光并以更高波长发射的化合物,从而产生可见荧光。它们是生物学研究中的重要工具,用于标记和检测蛋白质、核酸和细胞等生物分子,从而在显微镜、流式细胞术和实时荧光定量 PCR 等应用中实现灵敏和精确的可视化。

● 点击化学试剂:具有高特异性和最少的副产物,简化了复杂的合成过程。因此,它们在分子生物学、材料科学和药物化学中发挥着至关重要的作用。

● 聚合物聚乙二醇:多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 可裂解连接子:一类重要的分子,广泛应用于药物发现、化学生物学和材料科学等各个领域。这些连接子充当两个或多个分子实体之间的连接桥,可以在特定条件下选择性地裂解,从而释放附着的分子。这一特性使它们成为生物活性化合物靶向药物递送、成像和控释的有吸引力的工具。

● 抗体及抗体-药物偶联物及细胞生物学试剂:种类丰富可选择。

● ADC有效载荷:作为 ADC 的三个主要成分之一,有效载荷是高活性和有毒的药物分子,通过化学连接子附着在抗体上。有效载荷可以是小分子、蛋白质毒素、生物活性肽、酶,甚至放射性核素。通过适当的接头与适当的载体系统耦合的有效载荷可能会显示出靶向药物递送的特异性和有效性的提高。

● 脱氧核糖核酸:DNA 是脱氧核糖核酸的缩写,是一种包含所有生物体发育和功能的遗传指令的分子。DNA 由四个基本组成部分组成,称为核苷酸,由糖、磷酸基团和含氮碱基组成。

● 改性剂:改变其他分子或材料特性的化合物。在药物研发领域,改性剂在新型药物递送系统和生物医学设备的设计和优化中发挥着至关重要的作用。一种常见的改性剂类型是官能团,它是赋予分子特定化学和物理性质的原子的特定排列。

● 探针:AxisPharm 提供各种靶标特异性探针,例如叶酸 PEG、生物素 PEG、PROTAC PEG、荧光染料探针和图像探针。探针是一类含有官能团的化合物,旨在选择性地与生物分子(如酶、受体和核酸)相互作用。这些官能团包括荧光染料、生物素和亲和标签等,可以检测和定量复杂生物系统中的特定分子。


Different Types of Polyethylene Glycol PEG Linkers in Stock
Acid PEGDiketone PEGNon-PEG linkerPFP ester PEGSugar PEG β-Glucuronide Linker
Aldehyde PEGDNP PEGPEG-t-butyl esterPhosphonate PEGSulfonic acid PEG
Alkyne PEGDBCO PEGPEG-X-PEGPolymer PEGTCO PEG
Amino PEGDSPE PEGPeptide LinkersPropargyl PEGTetrazine PEG
Aminooxy PEGFluorescent PEGLipid PEGPROTAC LinkerHomobifunctional PEG
Azide PEGFmoc PEGM-PEGSilane PEGBromo PEG
BCN-PEGFolate PEGMaleimide PEGSPDP PEGTosylate PEG
Benzyl-PEGThiol PEGMeNH-PEGBranched PEGBis-Sulfone PEG
Biotin PEGHydrazide PEGNHS ester PEGHyNic PEGDOTA Reagent DOTA PEG
Bis-PEG-acidHydroxy PEGBoc-PEGBis-PEG-NHSIodo PEG
Bis-PEG-NHSCleavable Linkers


Lipids for Drug Delivery
Biotinyl Cap PEDodecanyl PEOther LipidPhosphatidylcholinePhosphatidylethanolamine
Biotinyl PEGlutaryl PEPDP PEPhosphoglycerolPtd Thioethanol
Caproylamine PEIonizable LipidPE MCCPhosphoserineSuccinyl PE
Cationic LipidLipid PEGCyanur PEMPB PE
Fluorescent Dye
AF DyesCyanine DyesMB DyesRhodamine DyeRox (carboxy-X-rhodamine) Dye
APDye FluorsDNP PEGJOER6GPeptide Labeling Reagents
Bodipy ProbesFluorescein (FAM)Pyrene ProbesTAMRA DyeClassic Fluorescent Dyes
IR FluorsQuenchersCoumarin 343

Click Chemistry Tools & Reagents
Alkyne PEGBCN-PEGPTAD LinkerTetrazine PEGClick Chemistry Auxiliary Reagents
Azide PEGDBCO PEGTCO PEGMethylcyclopropene Linkers
Polymer PEG
AcrylateBiotinFmocLipoamideSilane
Active esterBocFolateMaleimideStearic acid
AldehydeCarboxylic acidguanlian1010MW 2000TCO
AmineCholesterolHydrazideMW 5000Thiol
AzideDBCOHydroxylPolysarcosine
Cleavable Linkers
-S-S-CleavablePC CleavableDisulfide LinkersDde Cleavable Linkersβ-Glucuronide Linkers
Cleavable Peptidediazo biotin probesDTSSP crosslinkerPhotocleavable Biotin
Antibody and Antibody Drug Conjugate (ADC)
InotuzumabTrastuzumabEnfortumabLabetuzumab govitecanMirvetuximab soravtansine (solution)
VobramitamabDisitamabMirzotamabLoncastuximab tesirineTrastuzumab deruxtecan (solution)
PolatuzumabOzuriftamabBrentuximabTrastuzumab deruxtecanADC Control Human IgG1-Deruxtecan (DAR 8)
GemtuzumabInebilizumabDatopotamabCofetuzumab pelidotinGlembatumumab vedotin
Daratumumab (PBS)DenintuzumabSacituzumab govitecanBelantamab mafodotinTrastuzumab duocarmazine
PraluzatamabNaratuximabTisotumabEnfortumab vedotin-ejfvTrastuzumab emtansine (solution)
LorvotuzumabRolinsatamabTrastuzumab emtansineTelisotuzumab vedotinEnfortumab vedotin-ejfv (solution)
IzeltabartMipasetamabDatopotamab deruxtecanGemtuzumab ozogamicinBrentuximab vedotin (solution)
LupartumabIladatuzumabORM-5029Cantuzumab ravtansineDepatuxizumab mafodotin
CantuzumabBriobaceptIfinatamab deruxtecanTusamitamab ravtansineADC Control Human IgG1-Deruxtecan (DAR 4)
LonigutamabTamrintamabTisotumab vedotinZilovertamab vedotinDepatuxizumab MMAE
MoxetumomabSacituzumabDisitamab vedotinPolatuzumab vedotinADC Control Human IgG1-vcMMAF
AzintuxizumabUpifitamabBelantamabPivekimabSacituzumab govitecan (solution)
LifastuzumabGlembatumumabPatritumab deruxtecanFarletuzumab ecteribulin
Payloads and Linker modified Payloads
ExatecanBelotecan HClSGD-1882Dolastatin 10MC-Val-Cit-PAB-Doxorubicin
SN 38GimatecanMMAFCalicheamicinGly3-Val-Cit-PAB-MMAE
AmrubicinTaltobulinAuristatin EEribulin MesylateSuO-Glu-Val-Cit-PAB-MMAE
Mitomycin CDxdChlorambucilSoblidotin (Auristatin PE)Fmoc-G-amino-CH2O acetyl-Exetecan
Deruxtecan analogLurtotecanPF-06380101Deruxtecan analog 2DM1-MCC-PEG3-Biotin
sulfo-SPDB-DM4Exatecan mesylateAuristatin FPaclitaxelGGFG-amino-CH2O-acetyl Exetecan
RubitecanMC-DM1MMAF-methyl esterMC-MMD10Mal-PEG8-Val-Cit-PAB-MMAE
(4-NH2)-ExatecanIrinotecanDoxorubicin-SMCCSPDB-DM4DBCO-PEG4-Val-Cit-PAB MMAF
TopotecanPNU-159682MMAD10-HydroxycamptothecinTopotecan Hydrochloride
CL2A-SN38DM47-Ethylcamptothecin

Cell Biology Reagents
Neuro-DiO, lipophilic tracerVU (5-Vinyl-uridine)CM-DiI, lipophilic tracerLumiTracker ER GreenER-Tracker Red (BODIPY TR Glibenclamide)
Annexin V-AF 647 conjugateDAPI, blue fluorescent nucleic acid stainPropidium IodideDeep-Red Fluorescent Nissl StainMitoCLox, mitochondrial lipid peroxidation probe
Annexin V-AF 488 conjugateLumiTracker Mito Rhodamine 123LumiTracker Mito Green FMRAPID DiI, lipophilic tracerLaurdan (6-Dodecanoyl-2-dimethylaminonaphthalene)
Annexin V, His TagThiazole OrangeSynaptoProbe® RedLumiTracker ER RedLinear Polyacrylamide for Nucleic Acid Precipitation
DiD, lipophilic tracerRH 237, potentiometric probeSynaptoProbe® GreenRAPID DiO, lipophilic tracerFluo-4 AM, green fluorescent calcium indicator
DiR, lipophilic tracerHoechst 33342, blue fluorescent nucleic acid stainLumiTracker® Mito Red FMDiI, lipophilic tracerYODi-1, green fluorescent nucleic acid stain
DNA
CPG solid supportsDNA StainsModified Triphosphatesphosphoramidite
Probes
Biotin PEGFolate PEGImage ProbesPROTAC Linker
Amine reactive Linkers
Acid PEGAldehyde PEGBromo PEGMaleimide PEGNHS ester PEG


▍AxisPharm提供的服务

● 蛋白质组学服务:提供质谱分析、蛋白质鉴定和定量服务。专注于生物标志物分析,帮助客户在复杂的生物样本中发现和验证潜在的生物标志物。

● 代谢组学服务:利用先进的LC-MS/MS技术进行代谢物分析,提供通路洞察,帮助客户理解代谢途径和生物过程。

● 高级LC-MS/MS服务:用于PK分析和HPLC分离,确保高精度和高效率的研究结果,提供PK/PD研究,支持药物开发和临床前研究。


▍AxisPharm部分产品列表


Cat#NameM.W.Purity
AP15197Exatecan435.45≥98%
AP15072SN 38392.4≥95%
AP15226Amrubicin483.47≥98%
AP15664Mitomycin C334.3≥98%
AP1520310-Hydroxycamptothecin364.35≥95%
AP152047-Ethylcamptothecin376.41≥95%
AP15210Rubitecan393.35≥95%
AP15211(4-NH2)-Exatecan403.43≥95%
AP15206Topotecan421.5≥95%
AP15207Topotecan Hydrochloride425.5≥95%
AP15202Belotecan HCl433.5≥95%
AP15208Gimatecan447.5≥95%
AP15227Taltobulin473.65≥99%
AP15201Dxd493.48≥95%
AP15209Lurtotecan518.56≥95%
AP15196Exatecan mesylate531.55≥98%
AP15200Deruxtecan analog 2579.58≥95%
AP15205Irinotecan586.68≥95%
AP15224PNU-159682641.62≥98.24%
AP15220Soblidotin (Auristatin PE)701.98≥95%
AP15225SGD-1882725.8≥98%
AP15213MMAF732≥95%
AP15216Auristatin E732≥95%
AP15311Chlorambucil304.21≥98
AP15219PF-06380101743.01≥95%
AP15214Auristatin F746≥95%
AP15215MMAF-methyl ester745.99≥98%
AP15187Doxorubicin-SMCC762.8≥98%
AP15217MMAD771.06≥98%




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艾美捷科技代理Peptides.de品牌全系列产品


Peptides.de是一家专注于高质量肽产品生产的的德国企业。公司创立于2001年,总部位于德国赫尼希斯多夫。从单一肽到百万级肽库,从线性链到环状结构,从短肽到超长序列,从粗品到高纯精肽,从修饰化到标记化,从天然氨基酸到非天然变体,Peptides.de提供全维度肽与肽模拟物解决方案,覆盖新抗原筛选、过继性免疫治疗、T细胞刺激实验、表位作图、ELISpot检测、药物发现及芯片技术等核心领域。


Peptides.de公司不仅生产肽,还自主开发用于肽合成的核心设备——肽合成机器人。凭借其专利技术超声肽合成平台 (USPS®),团队能够在短时间高效生产数百种肽,并精准实现客户所需的各种修饰。


Peptides.de.png


▍ReVacc Scientific公司产品

Peptides.de核心业务涵盖:目录肽现货供应、专属肽链定制合成、个性化肽池构建、高通量肽库开发、肽芯片制备服务、功能型修饰肽生产以及精密预分装服务。

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▍Peptides.de部分产品列表

品名货号规格
ADV hexon (HLA-B*35:01)EP07882_11 mg;5 mg
ADV hexon 114 -124 (HLA-B*07:02)EP07881_11 mg;5 mg
ADV hexon 37-45 (HLA-A*24:02)EP07880_11 mg;5 mg
ADV hexon 886-894 (HLA-A*01:01)EP10774_11 mg;5 mg
ADV Hexon 917-925 (HLA-A*02:01)EP07914_11 mg;5 mg
BKV VP1 108-116 (HLA-A*02:01)EP11456_11 mg;5 mg
BRLF1 109-117 (HLA-A*02:01)EP11139_11 mg;5 mg
Chlamydia trachomatis MOMP 258-266 (HLA-A*02:01)EP11114_11 mg;5 mg
EBNA 3a (596-604)EP10789_11 mg;5 mg
EBNA-1 Protein (562-570)EP04510_11 mg;5 mg
EBV BALF-4 276-284 (HLA-A*02:01)EP11237_11 mg;5 mg
EBV BMLF-1 280-288 (HLA-A*02:01)EP07604_11 mg;5 mg
EBV BMRF1 116-128 (HLA-B*07:02)EP11138_11 mg;5 mg
EBV BMRF1 208-216 (HLA-A*02:01)EP11127_11 mg;5 mg
EBV BRLF-1 148-156 (HLA-A*03:01)EP11482_11 mg;5 mg
EBV BRLF1 101-109 (HLA-A*29:02)EP11142_11 mg;5 mg
EBV BRLF1 134-142 (HLA-A*11:01)EP11140_11 mg;5 mg
EBV BRLF1 28-37 (HLA-A*24:02)EP11141_11 mg;5 mg
EBV BZLF-1 190-197 (HLA-B*08:01)EP07899_11 mg;5 mg
EBV BZLF-1 54-64 (HLA-B*35:01)EP11143_11 mg;5 mg
EBV BZLF-1 54-64 mutant (HLA-B*35:01)EP11144_11 mg;5 mg
EBV BZLF1 44-52 (HLA-B*07:02)EP11214_11 mg;5 mg
EBV EBNA 3A 246-253 (HLA-A*24:02)EP11147_11 mg;5 mg
EBV EBNA 3B 399-408 (HLA-A*11:01)EP11150_11 mg;5 mg




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艾美捷科技代理Accuplexdiagnostics品牌全系列产品


Accuplex Diagnostics成立于2011年,是一家专注于开发新型诊断测试的企业,其目标市场涵盖兽医、人类和研究应用领域。在产品开发和国际营销积累了超过50年的丰富经验,致力于开发新的诊断测试,旨在简化已确定需求领域的生物标志物检测。Accuplex Diagnostics在爱尔兰梅努斯大学设有校内基地,为马匹和一般兽医实践提供测试套件,体现了其产学研结合的发展模式。

Accuplex Diagnostics的产品——OmniChek-SAA™通过检测血清淀粉样蛋白A(SAA)这一炎症生物标志物能快速检测多物种炎症情况,并具有以下特征:

● 广泛适用性:可检测多种物种的炎症情况,包括狗、兔子、猫、海豹、狒狒、猴子以及生产动物等。在兽医临床、动物研究以及生产动物健康管理等多个领域有重要的应用价值。

● 快速简便:运行快速且操作简单,只需使用一滴全血即可方便地使用,大大节省了检测时间和操作成本。

● 多场景应用:除了动物检测外,还可应用于其他重要领域,为兽医、动物主人和其他相关利益者提供了一个有用的新工具,有助于及时发现和处理动物的健康问题。


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▍Accuplexdiagnostics产品列表


品名产品描述
EquiChek™-SAAEquiChek™-SAA is a simple stall-side test that provides veterinarians, trainers or breeders with the opportunity to test for any inflammatory condition, including infections, where it matters, beside the horse. Blood can be analyzed without the need to send samples to a lab. In just two simple steps, you can tell if the horse has an active inflammatory condition.
OmniChek™-SAAOmniChek™-SAA is a simple animal-side test that provides veterinarians or animal carers and owners with the opportunity to test for inflammatory conditions, including infections, where and when it matters, beside the animal in the surgery, field, or home. All that is needed is a tiny drop of blood and analysis is performed without the need of a laboratory. In just two simple steps, you can tell if the animal has an active inflammatory condition such as acute infection.
SideroTec™-Total Assay KitThe SideroTec-Total kits contains all the reagents required for Siderophore detection with sufficient materials to run up to 110 tests. It can be used for both qualitative as well as quantitative assay and can be used either manually or automated for high throughput screening. With minimal set up and rapid assay time, the SideroTec-Total assay kit is a convenient and cost-effective method for siderophore detection.
SideroTec-HiSens™ AssayThe SideroTec-HiSens™ assay uses a single addition ready-to-use fluorescent label for detection of siderophores and other iron chelation molecules in aqueous, organic, or biological  samples.
SideroTec-AsP™The SideroTec-AsP™ is an ELISA* that enables detection of the fungus Aspergillus fumigatus responsible for Invasive Aspergillosis (IA), an infection which can prove fatal to patients with other underlying conditions including those with cancer, organ transplant patients or anyone who may be immunocompromised. It is now recognised that many patients with COPD also have invasive pulmonary aspergillosis but remain undetected.During the Covid pandemic, IA caused up to 30% of all deaths in ICU.


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Mirus Bio公司是世界上最早开发高效、低细胞毒性转染试剂的公司之一,同时也是目前该类试剂最主要的供应商之一。Mirus Bio的大部分转染试剂可以在含有血清的培养基中进行转染,省去了更换培养基的麻烦。TransIT-L1是Mirus产品的王牌,自1995年开发出来就申请了美国专利(US 5,744,335)。该项专利技术后来License给了Roche公司,以Fugene 6的品牌对外销售。TransIT-TKO & siQUEST转染试剂是常规siRNA转染试剂的王牌,与脂质体介导的转染试剂相比,该转染试剂可以高效转染siRNA,并且极大地降低了细胞的损伤程度。该试剂与siRNA混合转染细胞时,可以特异性剔除某些基因的表达,用于siRNA介导的基因沉默现象的研究。TransIT-Oligo转染试剂是即用型试剂,可以高效地将各种类型的寡聚核苷酸和寡聚脱氧核苷酸转染至受体细胞中。

 

此外,Mirus Bio还开发了专门针对特殊细胞的体外转染试剂,例如分别针对Jurkat,COS,3T3等细胞的转染试剂。Mirus Bio的科学家们新近开发了一种新的DNA转染试剂:TransITTM-2020 Transfection Reagent。TransITTM的性能优于FuGENETM、LipofectamineTM 2000和 LipofectamineTM 2000 CD;可在多种类型的细胞(包括难转染细胞)中实现高表达。

 

Mirus was founded on the principle that non-viral (i.e. plasmid DNA based) methods offer distinct advantages over viral methods of gene transfer. Our initial breakthrough in 1996 came with the development of a new type of transfection reagent that combined high efficiency delivery with low cellular toxicity: TransIT®-LT1 (Low Toxicity) Reagent remains the “gold standard” for broad-based gene delivery applications.

 

Mirus Bio公司主要产品:

Transfection with TransIT

Ingenio® Electroporation

Virus Production

Labeling with Label IT®

In Vivo Delivery

Accessory Products


品名货号
Human IgG1 Expression Control – 100 ugMIR 6250
Ingenio EZporator Electroporation SystemMIR 51000
Label IT Nucleic Acid Labeling Kit, Amine – sufficient for modifying 25 µg of nucleic acidMIR 3925
Label IT Nucleic Acid Labeling Kit, Amine – sufficient for modifying 100 µg of nucleic acidMIR 3900
TransIT-2020 Transfection Reagent – 0.4 mLMIR 5404
TransIT-2020 Transfection Reagent – 1.0 mLMIR 5400
TransIT-2020 Transfection Reagent – 10 X 1.0 mLMIR 5406
TransIT-2020 Transfection Reagent – 5 X 1.0 mLMIR 5405
TransIT-293  Transfection Reagent – 0.4 mLMIR 2704
TransIT-293 Transfection Reagent – 1.0 mLMIR 2700
TransIT-293 Transfection Reagent – 10 X 1.0 mLMIR 2706
TransIT-293 Transfection Reagent – 5 X 1.0 mLMIR 2705
TransIT-CHO  Transfection Kit – 10 X 1.0 mLMIR 2176
TransIT-CHO  Transfection Kit – 5 X 1.0 mLMIR 2175
TransIT-CHO Transfection Kit – 1.0 mLMIR 2170
TransIT-HeLaMONSTER Transfection Kit – 0.4 mLMIR 2904
TransIT-HeLaMONSTER Transfection Kit – 1.0 mLMIR 2900
TransIT-HeLaMONSTER Transfection Kit – 10 X 1.0 mLMIR 2906
TransIT-HeLaMONSTER Transfection Kit – 5 X 1.0 mLMIR 2905
TransIT-Insect Transfection Reagent – 0.4 mLMIR 6104
TransIT-Insect Transfection Reagent – 1.0 mLMIR 6100
TransIT-Insect Transfection Reagent – 10 X 1.0 mLMIR 6106
TransIT-Insect Transfection Reagent – 5 X 1.0 mLMIR 6105
TransIT-Jurkat Transfection Reagent – 0.4 mLMIR 2124
TransIT-Jurkat Transfection Reagent – 1.0 mLMIR 2120
TransIT-Jurkat Transfection Reagent – 10 X 1.0 mLMIR 2126
TransIT-Jurkat Transfection Reagent – 5 X 1.0 mLMIR 2125
TransIT-Keratinocyte Transfection Reagent – 0.4 mLMIR 2804
TransIT-Keratinocyte Transfection Reagent – 1.0 mLMIR 2800
TransIT-Keratinocyte Transfection Reagent – 10 X 1.0 mLMIR 2806
TransIT-Keratinocyte Transfection Reagent – 5 X 1.0 mLMIR 2805
TransIT-LT1 Transfection Reagent – 0.4 mLMIR 2304
TransIT-LT1 Transfection Reagent – 5 X 1.0 mLMIR 2305
TransIT-mRNA Transfection Kit – 0.4 mLMIR 2225
TransIT-mRNA Transfection Kit – 1.0 mLMIR 2250
TransIT-mRNA Transfection Kit – 10 X 1.0 mLMIR 2256
TransIT-mRNA Transfection Kit – 5 X 1.0 mLMIR 2255
TransIT-Oligo Transfection Reagent – 0.4 mLMIR 2164
TransIT-Oligo Transfection Reagent – 1.0 mLMIR 2160
TransIT-Oligo Transfection Reagent – 10 X 1.0 mLMIR 2166
TransIT-Oligo Transfection Reagent – 5 X 1.0 mLMIR 2165
TransIT-PRO Transfection Kit – 1.0 mL (with boost)MIR 5700
TransIT-PRO Transfection Kit – 10 mL (with boost)MIR 5760
TransIT-PRO Transfection Reagent – 1 mL (without boost)MIR 5740
TransIT-PRO Transfection Reagent – 10 mL (without boost)MIR 5750
TransIT-siQUEST Transfection Reagent – 0.4 mLMIR 2114
TransIT-siQUEST Transfection Reagent – 1.5 mLMIR 2110
TransIT-siQUEST Transfection Reagent – 10 X 1.5 mLMIR 2116
TransIT-siQUEST Transfection Reagent – 5 X 1.5 mLMIR 2115
TransIT-TKO Transfection Reagent – 0.4 mLMIR 2154
TransIT-TKO Transfection Reagent – 1.5 mLMIR 2150
TransIT-TKO Transfection Reagent – 10 X 1.5 mLMIR 2156
TransIT-TKO Transfection Reagent – 5 X 1.5 mLMIR 2155
TransIT-X2 Dynamic Delivery System – 0.3 mLMIR 6003
TransIT-X2 Dynamic Delivery System – 0.75 mLMIR 6004
TransIT-X2 Dynamic Delivery System – 1.5mLMIR 6000
TransIT-X2 Dynamic Delivery System – 10 X 1.5 mLMIR 6006
TransIT-X2 Dynamic Delivery System – 5 X 1.5 mLMIR 6005
Ingenio Electroporation Accessory – Cell Droppers (50 pk)MIR 50125
Ingenio Electroporation Solution Only – 25 rxns (6.25 mL)MIR 50111
Label IT Nucleic Acid Labeling Kit, Biotin – labels 100 µg nucleic acidMIR 3400
Label IT Plasmid Delivery Control, Cy3 – 10 µgMIR 7904
Label IT RNAi Delivery Control, Cy3 – 10 µg (0.75 nmol)MIR 7900
TransduceIT Transduction Reagent – 1 mLMIR 6620
TransIT-BrCa Reagent Transfection Reagent – 0.4 mLMIR 5504
Ingenio Electroporation Accessory – 0.4 cm Cuvettes (50 pk)MIR 50123
Ingenio Electroporation Solution Only – 50 rxns (12.5 mL)MIR 50114
Label IT Nucleic Acid Labeling Kit, Biotin – labels 25 µg nucleic acidMIR 3425
Label IT Plasmid Delivery Control, Cy3 – 100 µgMIR 7905
Label IT RNAi Delivery Control, Cy3 – 100 µg (7.5 nmol)MIR 7901
Label IT siRNA Tracker Intracellular Localization Kit, CX-Rhodamine – labels 50 µg siRNAMIR 7214
Label IT Tracker Intracellular Nucleic Acid Localization Kit, CX-Rhodamine – labels 50-200 µg plasmid DNAMIR 7022
Lentivirus Packaging Mix – 34 rxnMIR 6640
TransIT-BrCa Reagent Transfection Reagent – 1.0 mLMIR 5500
TransIT-LT1 Transfection Reagent – 1.0 mLMIR 2300
Ingenio Electroporation Accessory – 0.2 cm Cuvettes (50 pk)MIR 50121
Ingenio Electroporation Solution Only – 100 rxns (25 mL)MIR 50117
Label IT Nucleic Acid Labeling Kit, CX-Rhodamine – labels 100 µg nucleic acidMIR 3100
Label IT Plasmid Delivery Control, Fluorescein – 10 µgMIR 7906
Label IT RNAi Delivery Control, Fluorescein – 10 µg (0.75 nmol)MIR 7902
Label IT siRNA Tracker Intracellular Localization Kit, Cy3 – labels 50 µg siRNAMIR 7212
Label IT Tracker Intracellular Nucleic Acid Localization Kit, Cy3 – labels 50-200 µg plasmid DNAMIR 7020
Lentivirus Packaging Mix – 5 rxnMIR 6630
TransIT-BrCa Transfection Reagent – 5 x 1.0 mLMIR 5505
Ingenio Electroporation Kit, for Amaxa – 25 rxns (0.2 cm Cuvettes/Droppers)MIR 50112
Label IT Nucleic Acid Labeling Kit, CX-Rhodamine – labels 25 µg nucleic acidMIR 3125
Label IT Plasmid Delivery Control, Fluorescein – 100 µgMIR 7907
Label IT RNAi Delivery Control, Fluorescein – 100 µg (7.5 nmol)MIR 7903
Label IT siRNA Tracker Intracellular Localization Kit, Cy5 – labels 50 µg siRNAMIR 7213
Label IT Tracker Intracellular Nucleic Acid Localization Kit, Cy5 – labels 50-200 µg plasmid DNAMIR 7021
TransIT Lentivirus System – 34 rxnMIR 6655
TransIT-BrCa Transfection Reagent – 10 x 1.0 mLMIR 5506
TransIT-LT1 Transfection Reagent – 10 X 1.0 mLMIR 2306
Ingenio Electroporation Kit, for Amaxa – 50 rxns (0.2 cm Cuvettes/Droppers)MIR 50115
Label IT Nucleic Acid Labeling Kit, Cy3 – labels 100 µg nucleic acidMIR 3600
Label IT siRNA Tracker Intracellular Localization Kit, Fluorescein – labels 50 µg siRNAMIR 7216
Label IT Tracker Intracellular Nucleic Acid Localization Kit, Fluorescein – labels 50-200 µg plasmid DNAMIR 7025
TransIT Lentivirus System – 5 rxnMIR 6650
Ingenio Electroporation Kit, for Amaxa – 100 rxns (0.2 cm Cuvette/Droppers)MIR 50118
Label IT Nucleic Acid Labeling Kit, Cy3 – labels 25 µg nucleic acidMIR 3625
TransIT-Lenti Transfection Reagent – 10 x 1.5 mLMIR 6606
Ingenio Electroporation Kit, for other Electroporators – 25 rxns, (0.4 cm Cuvettes/Droppers)MIR 50113
Label IT Nucleic Acid Labeling Kit, Cy5 – labels 100 µg nucleic acidMIR 3700
TransIT-Lenti Transfection Reagent – 1.5 mLMIR 6600
Ingenio Electroporation Kit, for other Electroporators – 50 rxns (0.4 cm Cuvettes/Droppers)MIR 50116
Label IT Nucleic Acid Labeling Kit, Cy5 – labels 25 µg nucleic acidMIR 3725
TransIT-Lenti Transfection Reagent – 0.75 mLMIR 6604
Ingenio Electroporation Kit, for other Electroporators – 100 rxns (0.4 cm Cuvette/Droppers)MIR 50119
TransIT-Lenti Transfection Reagent – 5 x 1.5 mLMIR 6605
TransIT-Lenti Transfection Reagent – 0.3 mLMIR 6603
Label IT Nucleic Acid Labeling Kit, DNP – labels 100 µg nucleic acidMIR 3800
Label IT Nucleic Acid Labeling Kit, DNP – labels 25 µg nucleic acidMIR 3825
Label IT Nucleic Acid Labeling Kit, Fluorescein – labels 100 µg nucleic acidMIR 3200
Label IT Nucleic Acid Labeling Kit, Fluorescein – labels 25 µg nucleic acidMIR 3225
Label IT Nucleic Acid Labeling Kit, MFP488 – labels 100 µg nucleic acidMIR 7100
Label IT Nucleic Acid Labeling Kit, MFP488 – labels 25 µg nucleic acidMIR 7125
TransIT-EE Delivery Solution – 40 InjectionsMIR 5340
TransIT-QR Delivery Solution – 40 InjectionsMIR 5240
pLIVE Vector – 20 ugMIR 5420
pLIVE Vector/LacZ – 20 ug of each vectorMIR 5520
pLIVE Vector/SEAP Control Vector Kit – 20 ug of each vectorMIR 5620
pLIVE Vector Complete System – 20 ug of each vectorMIR 5320
RevIT AAV Enhancer – 1.5 mL (for 1 L of cell culture)MIR 8000
TransIT-VirusGEN GMP Transfection Reagent – 150 mLMIR 6845-GMP
VirusGEN AAV Transfection Kit – 150mLMIR 6755
VirusGEN AAV Transfection Kit, 1 Kit – for 10 L of cell cultureMIR 6745
RevIT AAV Enhancer – 10 x 1.5 mL (for 10 L of cell culture)MIR 8006
RevIT AAV Enhancer – 75 mL (for 50 L of cell culture)MIR 8080
VirusGEN GMP LV Transfection KitMIR 6825-GMP
VirusGEN LV Transfection KitMIR 6760
VirusGEN AAV Kit + RevIT for 10L CultureMIR 8008
VirusGEN GMP AAV Transfection KitMIR 6815-GMP
VirusGEN AAV Transfection Kit – 1 Kit for 1 L of cell cultureMIR 6750
VirusGEN AAV Kit + RevIT for 1L CultureMIR 8007
TransIT-VirusGEN Transfection Reagent – 150 mLMIR 6740
TransIT-VirusGEN Transfection Reagent – 30 mLMIR 6720
TransIT-VirusGEN Transfection Reagent – 10 x 1.5 mLMIR 6706
TransIT-VirusGEN Transfection Reagent – 5 x 1.5 mLMIR 6705


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全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com


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